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Once inorganic selenium enters the cell, it may be reduced to hydrogen selenide (H 2 Se) by glutathione (GSH) ( Selenoproteins are a unique class of proteins containing the rare amino acid selenocysteine (Sec), often hailed as the 21st proteinogenic amino acid

OAT2 encodes a key renal solute transport protein, and genetic variations of TBX2 are a determinant of CKD (Kato et al., 2015)

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